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ITN0110

ITN0110
  • Catalog: ITN0110
  • Gene/Protein: ZBTB17 MIZ1 ZNF151 ZNF60
  • Product Description: Immunotag™ ZBT17 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ ZBT17 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein ZBT17
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein . at AA range: 160-240
Specificity ZBT17 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name ZBTB17 MIZ1 ZNF151 ZNF60
Accession No. Q13105 Q60821
Description zinc finger and BTB domain containing 17(ZBTB17) Homo sapiens This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Cell_Cycle_G1S,Cell_Cycle_G2M_DNA,
Protein Expression Brain,Cervix carcinoma,Insulinoma,Placenta,
Subcellular Localization nucleoplasm,
Protein Function function:May function as a housekeeping DNA-binding protein that regulates the expression of specific genes. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Also has potent growth arrest activity, probably through inhibition of cell cycle progression. Required for early embryonic development during gastrulation.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 13 C2H2-type zinc fingers.,subunit:Binds to the C-terminal helix-loop-helix motif of MYC which inhibits ZBTB17 transactivation and growth arrest activities and renders it insoluble in the nucleus. Also interacts with HCFC1, MAGEA4 and TMPRSS11A.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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