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ITN0147

ITN0147
  • Gene/Protein: ZMAT3 PAG608 WIG1
  • Product Description: Immunotag™ ZMAT3 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ ZMAT3 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein ZMAT3
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 210-290
Specificity ZMAT3 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name ZMAT3 PAG608 WIG1
Accession No. Q9HA38 O54836 O08781
Description zinc finger matrin-type 3(ZMAT3) Homo sapiens This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category p53,
Protein Expression Lung carcinoma,Mammary gland,Testis,
Subcellular Localization nucleolus,
Protein Function function:Acts as a bona fide target gene of p53. May play a role in the p53-dependent growth regulatory pathway. May contribute to p53-mediated apoptosis by regulation of p53 expression and translocation to the nucleus and nucleolus.,induction:By DNA damage in a p53-dependent manner. Up-regulated following ionizing radiation in primary squamous cell carcinoma of the lung and in various colon cancer cell lines.,similarity:Contains 3 matrin-type zinc fingers.,subunit:Interacts with dsRNA.,tissue specificity:Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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