ITN0168
ITN0168
- Catalog: ITN0168
- Gene/Protein: COL9A2
- Product Description: Immunotag™ CO9A2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CO9A2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 540-620 |
| Specificity | CO9A2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | COL9A2 |
| Accession No. | Q14055 Q07643 |
| Description | collagen type IX alpha 2 chain(COL9A2) Homo sapiens This gene encodes one of the three alpha chains of type IX collagen, the major collagen component of hyaline cartilage. Type IX collagen, a heterotrimeric molecule, is usually found in tissues containing type II collagen, a fibrillar collagen. This chain is unusual in that, unlike the other two type IX alpha chains, it contains a covalently attached glycosaminoglycan side chain. Mutations in this gene are associated with multiple epiphyseal dysplasia. [provided by RefSeq, Jul 2008], |
| Protein Expression | Cartilage,Foreskin, |
| Subcellular Localization | extracellular region,proteinaceous extracellular matrix,collagen trimer,collagen type IX trimer,endoplasmic reticulum lumen, |
| Protein Function | disease:Defects in COL9A2 are the cause of multiple epiphyseal dysplasia type 2 (EDM2) [MIM:600204]. EDM is a generalized skeletal dysplasia associated with significant morbidity. Joint pain, joint deformity, waddling gait, and short stature are the main clinical signs and symptoms. EDM is broadly categorized into the more severe Fairbank and the milder Ribbing types. EDM2 inheritance is autosomal dominant.,disease:Defects in COL9A2 may be a cause of susceptibility to intervertebral disc disease (IDD) [MIM:603932]. IDD is one of the most common musculo-skeletal disorders.,function:Structural component of hyaline cartilage and vitreous of the eye.,PTM:Covalently linked to the telopeptides of type II collagen by lysine-derived cross-links.,PTM:Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.,similarity:Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.,subunit:Heterotrimer of an alpha 1(IX), an alpha 2(IX) and an alpha 3(IX) chain., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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