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ITN0171

ITN0171
  • Gene/Protein: CD320 8D6A UNQ198/PRO224
  • Product Description: Immunotag™ CD320 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ CD320 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CD320
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 100-180
Specificity CD320 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name CD320 8D6A UNQ198/PRO224
Accession No. Q9NPF0 Q9Z1P5 Q5HZW5
Description CD320 molecule(CD320) Homo sapiens This gene encodes the transcobalamin receptor that is expressed at the cell surface. It mediates the cellular uptake of transcobalamin bound cobalamin (vitamin B12), and is involved in B-cell proliferation and immunoglobulin secretion. Mutations in this gene are associated with methylmalonic aciduria. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011],
Protein Expression Brain,Coronary artery,Kidney,Mammary gland,
Subcellular Localization endoplasmic reticulum,plasma membrane,endosome membrane,membrane,integral component of membrane,extracellular exosome,
Protein Function function:Germinal center-B (GC-B) cells differentiate into memory B-cells and plasma cells (PC) through interaction with T-cells and follicular dendritic cells (FDC). CD320 augments the proliferation of PC precursors generated by IL-10. Receptor for the cellular uptake of transcobalamin bound cobalamin.,similarity:Contains 2 LDL-receptor class A domains.,tissue specificity:Expressed abundantly on follicular dendritic cells (FDCs).,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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