ITN0318
ITN0318
- Catalog: ITN0318
- Gene/Protein: NKAP
- Product Description: Immunotag™ NKAP Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | NKAP |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 10-90 |
Specificity | NKAP Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | NKAP |
Accession No. | Q8N5F7 Q9D0F4 Q4V7C9 |
Description | NFKB activating protein(NKAP) Homo sapiens This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010], |
Protein Expression | B-cell,Cervix,Epithelium,Hepatocyte,Placenta,Small intestine,Testis, |
Subcellular Localization | nucleoplasm,cytoplasm, |
Protein Function | function:Regulator of TNF and IL-1 induced NF-kappa-B activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the UPF0396 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |