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ITN0318

ITN0318
  • Catalog: ITN0318
  • Gene/Protein: NKAP
  • Product Description: Immunotag™ NKAP Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ NKAP Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein NKAP
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 10-90
Specificity NKAP Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name NKAP
Accession No. Q8N5F7 Q9D0F4 Q4V7C9
Description NFKB activating protein(NKAP) Homo sapiens This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010],
Protein Expression B-cell,Cervix,Epithelium,Hepatocyte,Placenta,Small intestine,Testis,
Subcellular Localization nucleoplasm,cytoplasm,
Protein Function function:Regulator of TNF and IL-1 induced NF-kappa-B activation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the UPF0396 family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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