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ITN0648

ITN0648
  • Catalog: ITN0648
  • Gene/Protein: GINS1 KIAA0186 PSF1
  • Product Description: Immunotag™ PSF1 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ PSF1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PSF1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity PSF1 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name GINS1 KIAA0186 PSF1
Accession No. Q14691 Q9CZ15
Description GINS complex subunit 1(GINS1) Homo sapiens The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4; MIM 610611), Psf1, Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).[supplied by OMIM, Mar 2008],
Protein Expression Bone marrow,Skin,
Subcellular Localization GINS complex,nucleus,nucleoplasm,cytoplasm,
Protein Function function:The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. GINS1 is essential for function.,induction:Significantly up-regulated in agressive melanomas.,mass spectrometry:This is the measured mass for the GINS complex PubMed:17557111,similarity:Belongs to the GINS1/PSF1 family.,subunit:Component of the GINS complex which is a heterotetramer of GINS1, GINS2, GINS3 and GINS4. Forms a stable subcomplex with GINS4. GINS complex interacts with DNA primase in vitro.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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