ITN0662
ITN0662
- Catalog: ITN0662
- Gene/Protein: POLR3K RPC11 My010
- Product Description: Immunotag™ RPC10 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | RPC10 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | RPC10 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | POLR3K RPC11 My010 |
Accession No. | Q9Y2Y1 Q9CQZ7 |
Description | RNA polymerase III subunit K(POLR3K) Homo sapiens This gene encodes a small essential subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The carboxy-terminal domain of this subunit shares a high degree of sequence similarity to the carboxy-terminal domain of an RNA polymerase II elongation factor. This similarity in sequence is supported by functional studies showing that this subunit is required for proper pausing and termination during transcription. Pseudogenes of this gene are found on chromosomes 13 and 17.[provided by RefSeq, Jul 2010], |
Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism,RNA polymerase,Cytosolic DNA-sensing pathway, |
Protein Expression | Fetal brain,Uterus, |
Subcellular Localization | nucleoplasm,DNA-directed RNA polymerase III complex,nucleolus,cytosol, |
Protein Function | function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.,similarity:Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.,similarity:Contains 1 TFIIS-type zinc finger.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |