ITN0663
ITN0663
- Catalog: ITN0663
- Gene/Protein: POLR3F
- Product Description: Immunotag™ RPC6 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | RPC6 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | RPC6 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | POLR3F |
Accession No. | Q9H1D9 Q921X6 |
Description | RNA polymerase III subunit F(POLR3F) Homo sapiens The protein encoded by this gene is one of more than a dozen subunits forming eukaryotic RNA polymerase III (RNA Pol III), which transcribes 5S ribosomal RNA and tRNA genes. This protein has been shown to bind both TFIIIB90 and TBP, two subunits of RNA polymerase III transcription initiation factor IIIB (TFIIIB). Unlike most of the other RNA Pol III subunits, the encoded protein is unique to this polymerase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], |
Cell Pathway/ Category | Purine metabolism,Pyrimidine metabolism,RNA polymerase,Cytosolic DNA-sensing pathway, |
Protein Expression | Brain,Kidney,Synovial membrane, |
Subcellular Localization | nucleoplasm,DNA-directed RNA polymerase III complex,cytosol, |
Protein Function | function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex.,similarity:Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits. RPC3/POLR3C, RPC6/POLR3F and RPC7/POLR3G form a Pol III subcomplex (By similarity). Interacts with TBP and TFIIIB90 and GTF3C4., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |