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ITN0719

ITN0719
  • Gene/Protein: FYCO1 ZFYVE7
  • Product Description: Immunotag™ FYCO1 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ FYCO1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein FYCO1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity FYCO1 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name FYCO1 ZFYVE7
Accession No. Q9BQS8 Q8VDC1
Description FYVE and coiled-coil domain containing 1(FYCO1) Homo sapiens This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011],
Protein Expression Heart,Lung,Ovary,Skeletal muscle,Skin,Spleen,
Subcellular Localization lysosome,late endosome,autophagosome,membrane,integral component of membrane,cytoplasmic vesicle,intracellular membrane-bounded organelle,
Protein Function PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 GOLD domain.,similarity:Contains 1 RUN domain.,tissue specificity:Expressed in heart and skeletal muscle.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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