ITN0814
ITN0814
- Catalog: ITN0814
- Gene/Protein: KIR2DS5 CD158G NKAT9
- Product Description: Immunotag™ KI2S5 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | KI2S5 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | KI2S5 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | KIR2DS5 CD158G NKAT9 |
| Accession No. | Q14953 |
| Description | killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 5(KIR2DS5) Homo sapiens Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the |
| Cell Pathway/ Category | Antigen processing and presentation,Natural killer cell mediated cytotoxicity, |
| Protein Expression | Lymphoid, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane, |
| Protein Function | function:Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.,similarity:Belongs to the immunoglobulin superfamily.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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