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ITN0992

ITN0992
  • Gene/Protein: NUP155 KIAA0791
  • Product Description: Immunotag™ NU155 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ NU155 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein NU155
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 840-920
Specificity NU155 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name NUP155 KIAA0791
Accession No. O75694 Q99P88 P37199
Description nucleoporin 155(NUP155) Homo sapiens Nucleoporins are proteins that play an important role in the assembly and functioning of the nuclear pore complex (NPC) which regulates the movement of macromolecules across the nuclear envelope (NE). The protein encoded by this gene plays a role in the fusion of NE vesicles and formation of the double membrane NE. The protein may also be involved in cardiac physiology and may be associated with the pathogenesis of atrial fibrillation. Alternative splicing results in multiple transcript variants of this gene. A pseudogene associated with this gene is located on chromosome 6. [provided by RefSeq, May 2013],
Protein Expression Brain,Testis,
Subcellular Localization nuclear envelope,nuclear pore,membrane,nuclear membrane,nuclear pore inner ring,
Protein Function function:Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport.,PTM:Phosphorylated. Phosphorylation and dephosphorylation may be important for the function of NUP155 and may play a role in the reversible disassembly of the nuclear pore complex during mitosis.,similarity:Belongs to the non-repetitive/WGA-negative nucleoporin family.,subcellular location:In mitosis, assumes a diffuse cytoplasmic distribution probably as a monomer, before reversing back into a punctate nuclear surface localization at the end of mitosis.,subunit:Interacts with GLE1 and NUP35/NUP53. Able to form a heterotrimer with GLE1 and NUPL2 in vitro.,tissue specificity:Expressed in all tissues tested, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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