ITN1097
ITN1097
- Catalog: ITN1097
- Gene/Protein: PRPF40A FBP11 FLAF1 FNBP3 HIP10 HYPA HSPC225
- Product Description: Immunotag™ PR40A Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | PR40A |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 450-530 |
| Specificity | PR40A Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | PRPF40A FBP11 FLAF1 FNBP3 HIP10 HYPA HSPC225 |
| Accession No. | O75400 Q9R1C7 |
| Description | domain:The WW domains are essential for localization to nuclear speckles.,function:Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 409.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the PRPF40 family.,similarity:Contains 2 WW domains.,similarity:Contains 5 FF domains.,subunit:Interacts with the N-terminus of HTT. Interacts with the phosphorylated carboxyterminal domain of POLR2A. Interacts with SF1, SRPK1 CARD8, ATBF1 and MECP2 (By similarity). Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP.,tissue specificity:Widely expressed., |
| Cell Pathway/ Category | Spliceosome, |
| Protein Expression | Epithelium,Frontal cortex,Liver,Lymphoma,Placenta,Smooth mu |
| Subcellular Localization | nucleoplasm,U1 snRNP,cytoplasm,membrane,nuclear matrix,nuclear speck,U2-type prespliceosome, |
| Protein Function | domain:The WW domains are essential for localization to nuclear speckles.,function:Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). May be involved in pre-mRNA splicing.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 409.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the PRPF40 family.,similarity:Contains 2 WW domains.,similarity:Contains 5 FF domains.,subunit:Interacts with the N-terminus of HTT. Interacts with the phosphorylated carboxyterminal domain of POLR2A. Interacts with SF1, SRPK1 CARD8, ATBF1 and MECP2 (By similarity). Interacts through the WW domains with formin proline-rich regions and with WASL/N-WASP.,tissue specificity:Widely expressed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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