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ITN1193

ITN1193
  • Catalog: ITN1193
  • Gene/Protein: PTPRB PTPB
  • Product Description: Immunotag™ PTPRB Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ PTPRB Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PTPRB
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein . at AA range: 280-360
Specificity PTPRB Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name PTPRB PTPB
Accession No. P23467 B2RU80
Description protein tyrosine phosphatase, receptor type B(PTPRB) Homo sapiens The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite gro
Cell Pathway/ Category Adherens_Junction,
Protein Expression Endometrium,Epithelium,Human fetal kidney,Placenta,Spleen,T
Subcellular Localization integral component of plasma membrane,receptor complex,
Protein Function catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,similarity:Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,similarity:Contains 17 fibronectin type-III domains.,subunit:Interacts with MAGI3.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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