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ITN1282

ITN1282
  • Gene/Protein: PPP3CC CALNA3 CNA3
  • Product Description: Immunotag™ PP2BC Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ PP2BC Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PP2BC
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity PP2BC Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name PPP3CC CALNA3 CNA3
Accession No. P48454 P48455
Description protein phosphatase 3 catalytic subunit gamma(PPP3CC) Homo sapiens Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Cell Pathway/ Category MAPK_ERK_Growth,MAPK_G_Protein,Calcium,Oocyte meiosis,Apoptosis_Inhibition,Apoptosis_Mitochondrial,Apoptosis_Overview,WNT,WNT-T CELLAxon guidance,VEGF,Natural killer cell mediated cytotoxicity,T_Cell_Receptor,B_Cell_Antigen,Long-term potentiation,Alzheimer's disease,Amyotrophic lateral sclerosis (ALS),
Protein Expression Endothelial cell,Testis,
Subcellular Localization mitochondrion,cytosol,extracellular exosome,
Protein Function catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 Fe(3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.,tissue specificity:Testis.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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