ITN1345
ITN1345
- Catalog: ITN1345
- Gene/Protein: SLC6A3 DAT1
- Product Description: Immunotag™ SC6A3 Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | SC6A3 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from part region of human protein |
Specificity | SC6A3 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | SLC6A3 DAT1 |
Accession No. | Q01959 Q61327 P23977 |
Description | solute carrier family 6 member 3(SLC6A3) Homo sapiens This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.[provided by RefSeq, Nov 2009], |
Cell Pathway/ Category | Parkinson's disease, |
Protein Expression | Brain,Pooled,Whole blood, |
Subcellular Localization | cytoplasm,plasma membrane,integral component of plasma membrane,cell surface,integral component of membrane,flotillin complex,axon,neuron projection,neuronal cell body,membrane raft,presynapse, |
Protein Function | function:Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.,miscellaneous:This protein is the target of psychomotor stimulants such as amphetamines or cocaine.,online information:Dopamine transporter entry,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,subunit:Homooligomer; disulfide-linked. Interacts with PRKCABP and TGFB1I1., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |