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ITN1452

ITN1452
  • Catalog: ITN1452
  • Gene/Protein: TNNC2
  • Product Description: Immunotag™ TNNC2 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ TNNC2 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein TNNC2
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity TNNC2 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name TNNC2
Accession No. P02585 P20801
Description troponin C2, fast skeletal type(TNNC2) Homo sapiens Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Calcium,
Protein Expression Liver,Muscle,Skeletal muscle,Tongue,
Subcellular Localization cytosol,troponin complex,
Protein Function function:Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.,miscellaneous:Skeletal muscle troponin C binds four calcium ions.,similarity:Belongs to the troponin C family.,similarity:Contains 4 EF-hand domains.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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