ITN1507
ITN1507
- Catalog: ITN1507
- Gene/Protein: ATP6V1A ATP6A1 ATP6V1A1 VPP2
- Product Description: Immunotag™ VATA Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | VATA |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | VATA Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | ATP6V1A ATP6A1 ATP6V1A1 VPP2 |
| Accession No. | P38606 P50516 |
| Description | ATPase H+ transporting V1 subunit A(ATP6V1A) Homo sapiens This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all |
| Cell Pathway/ Category | Oxidative phosphorylation,Vibrio cholerae infection,Epithelial cell signaling in Helicobacter pylori infection, |
| Protein Expression | Fetal adrenal gland,Hypothalamus,Kidney,Leukocyte, |
| Subcellular Localization | mitochondrion,lysosomal membrane,cytosol,plasma membrane,integral component of plasma membrane,microvillus,apical plasma membrane,proton-transporting two-sector ATPase complex,proton-transporting V-type ATPase, V1 domain,myelin sheath |
| Protein Function | catalytic activity:ATP + H(2)O + H(+)(In) = ADP + phosphate + H(+)(Out).,function:Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.,similarity:Belongs to the ATPase alpha/beta chains family.,subunit:V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (main components: subunits A, B, C, D, E, and F) attached to an integral membrane V0 proton pore complex (main component: the proteolipid protein).,tissue specificity:Present in all tissues analyzed., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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