ITN1523
ITN1523
- Catalog: ITN1523
- Gene/Protein: VDAC3
- Product Description: Immunotag™ VDAC3 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
|
| Target Protein | VDAC3 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Rat,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | VDAC3 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | VDAC3 |
| Accession No. | Q9Y277 Q60931 Q9R1Z0 |
| Description | voltage dependent anion channel 3(VDAC3) Homo sapiens This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011], |
| Cell Pathway/ Category | Calcium,Parkinson's disease,Huntington's disease, |
| Protein Expression | Skin,Umbilical cord blood, |
| Subcellular Localization | nucleus,mitochondrion,mitochondrial outer membrane,pore complex,extracellular exosome, |
| Protein Function | domain:Consists mainly of a membrane-spanning beta-barrel formed by 19 beta-strands.,function:Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.,similarity:Belongs to the eukaryotic mitochondrial porin family.,tissue specificity:Widely expressed. Highest in testis., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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