ITN1568
ITN1568
- Catalog: ITN1568
- Gene/Protein: CD27 TNFRSF7
- Product Description: Immunotag™ CD27 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CD27 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1-80 |
| Specificity | CD27 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | CD27 TNFRSF7 |
| Accession No. | P26842 P41272 |
| Description | CD27 molecule(CD27) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction, |
| Protein Expression | B-cell,Cervix carcinoma,Monocyte,Thymus, |
| Subcellular Localization | extracellular region,nucleus,plasma membrane,integral component of plasma membrane,external side of plasma membrane,neuron projection,extracellular exosome, |
| Protein Function | function:Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.,PTM:Phosphorylated and O-glycosylated.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Homodimer. Interacts with SIVA1 and TRAF2.,tissue specificity:Found in most T-lymphocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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