ITN1624
ITN1624
- Catalog: ITN1624
- Gene/Protein: CNBP RNF163 ZNF9
- Product Description: Immunotag™ CNBP Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CNBP |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 60-140 |
| Specificity | CNBP Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | CNBP RNF163 ZNF9 |
| Accession No. | P62633 P53996 P62634 |
| Description | CCHC-type zinc finger nucleic acid binding protein(CNBP) Homo sapiens This gene encodes a nucleic-acid binding protein with seven zinc-finger domains. The protein has a preference for binding single stranded DNA and RNA. The protein functions in cap-independent translation of ornithine decarboxylase mRNA, and may also function in sterol-mediated transcriptional regulation. A CCTG expansion from <30 repeats to 75-11000 repeats in the first intron of this gene results in myotonic dystrophy type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2016], |
| Protein Expression | Brain,Lung,Placenta,Synovial membrane tissue,Uterus |
| Subcellular Localization | nucleus,endoplasmic reticulum,cytosol, |
| Protein Function | disease:Defects in CNBP are the cause of myotonic dystrophy 2 (DM2) [MIM:602668]; also known as proximal myotonic myopathy (PROMM). DM2 is an autosomal dominant neurodegenerative disorder characterized by myotonia. DM2 is caused by a CCTG expansion (mean approximately 5000 repeats) located in intron 1 of the CNBP gene.,function:Single stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression.,similarity:Contains 7 CCHC-type zinc fingers.,tissue specificity:Present in all tissues examined., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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