menu
Your Cart

ITN1787

ITN1787
  • Gene/Protein: PLCB1 KIAA0581
  • Product Description: Immunotag™ PLCB1 Polyclonal Antibody
280.0000
Price in reward points: 294

Available Options

Immunotag™ PLCB1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PLCB1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity PLCB1 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name PLCB1 KIAA0581
Accession No. Q9NQ66 Q9Z1B3 P10687
Description phospholipase C beta 1(PLCB1) Homo sapiens The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Inositol phosphate metabolism,Calcium,Chemokine,Phosphatidylinositol signaling system,Vascular smooth muscle contraction,WNT,WNT-T CELLGap junction,Long-term potentiation,Long-term depression,GnRH,Melanogenesis,Alzheimer's disease,Huntington's disease,
Protein Expression Brain,Epithelium,Placenta,Testis,
Subcellular Localization nuclear chromatin,nucleus,cytoplasm,cytosol,nuclear speck,nuclear membrane,myelin sheath,extracellular exosome,
Protein Function catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.,cofactor:Calcium.,function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.,miscellaneous:The receptor-mediated activation of PLC-beta-1 is mediated by two G-protein alpha subunits, alpha-Q and alpha-11.,similarity:Contains 1 C2 domain.,similarity:Contains 1 PI-PLC X-box domain.,similarity:Contains 1 PI-PLC Y-box domain.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
English_US
Danish
Dutch
English_UK
French
German
Spanish
Norwegian
Portuguese
Finnish
Swedish
Polish

Write a review

Note: HTML is not translated!
Bad Good
Captcha

CONNECT WITH US