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ITN2147

ITN2147
  • Gene/Protein: FCRL1 FCRH1 IFGP1 IRTA5
  • Product Description: Immunotag™ FCRL1 Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ FCRL1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein FCRL1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity FCRL1 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name FCRL1 FCRH1 IFGP1 IRTA5
Accession No. Q96LA6 Q8R4Y0
Description Fc receptor like 1(FCRL1) Homo sapiens This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009],
Protein Expression Blood,Lymph node,Peripheral blood,Tonsil,
Subcellular Localization plasma membrane,integral component of membrane,
Protein Function function:May function as an activating coreceptor in B cells. May function in B cells activation and differentiation.,induction:Down-regulated in activated B cells.,PTM:Phosphorylated on tyrosines upon activation.,similarity:Contains 3 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Primarily expressed in secondary lymphoid tissues by mature subsets of B cells. Detected in spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. Specifically expressed by mature B lineage cells with higher expression in naive versus memory B cells (at protein level).,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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