ITN2185
ITN2185
- Catalog: ITN2185
- Gene/Protein: LYVE1 CRSBP1 HAR XLKD1 UNQ230/PRO263
- Product Description: Immunotag™ LYVE1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | LYVE1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | LYVE1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | LYVE1 CRSBP1 HAR XLKD1 UNQ230/PRO263 |
| Accession No. | Q9Y5Y7 Q8BHC0 |
| Description | lymphatic vessel endothelial hyaluronan receptor 1(LYVE1) Homo sapiens This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis. [provided by RefSeq, Jul 2008], |
| Protein Expression | Hippocampus,Liver,Placenta,Plasma, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,membrane,integral component of membrane,extracellular exosome, |
| Protein Function | function:Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.,PTM:O-glycosylated.,similarity:Contains 1 Link domain.,subcellular location:Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.,subunit:Homodimer; disulfide-linked. Interacts with PDGFB and IGFBP3. Forms a transient ternary complex with PDGFB and PDGFRB in TGN.,tissue specificity:Mainly expressed in endothelial cells lining lymphatic vessels., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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