ITN2280
ITN2280
- Catalog: ITN2280
- Gene/Protein: TNFRSF14 HVEA HVEM UNQ329/PRO509
- Product Description: Immunotag™ TNR14 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | TNR14 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 190-270 |
| Specificity | TNR14 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | TNFRSF14 HVEA HVEM UNQ329/PRO509 |
| Accession No. | Q92956 |
| Description | TNF receptor superfamily member 14(TNFRSF14) Homo sapiens This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction, |
| Protein Expression | Brain,Cervix adenocarcinoma,Skin, |
| Subcellular Localization | plasma membrane,integral component of plasma membrane,external side of plasma membrane,integral component of membrane, |
| Protein Function | function:Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.,PTM:N-glycosylated.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Interacts with TRAF2, TRAF3 and TRAF5.,tissue specificity:Widely expressed, with the highest expression in lung, spleen and thymus., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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