ITN2304
ITN2304
- Catalog: ITN2304
- Gene/Protein: NAAA ASAHL PLT
- Product Description: Immunotag™ NAAA Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | NAAA |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 230-310 |
Specificity | NAAA Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | NAAA ASAHL PLT |
Accession No. | Q02083 Q9D7V9 Q5KTC7 |
Description | N-acylethanolamine acid amidase(NAAA) Homo sapiens This gene encodes an N-acylethanolamine-hydrolyzing enzyme which is highly similar to acid ceramidase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
Protein Expression | Liver,Muscle,Placenta, |
Subcellular Localization | cytoplasm,lysosomal lumen,extracellular exosome,presynapse, |
Protein Function | enzyme regulation:Stimulated by DTT and Nonidet P-40.,function:Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-lauroylethanolamine = N-stearoylethanolamine > N-arachidonoylethanolamine > N-oleoylethanolamine. Also exhibits weak hydrolytic activity against the ceramides N-lauroylsphingosine and N-palmitoylsphingosine.,PTM:N-glycosylated. Tunicamycin treatment causes a reduction in specific activity against N-palmitoylethanolamine.,similarity:Belongs to the acid ceramidase family.,tissue specificity:Expressed in numerous tissues, with highest levels in liver and kidney, followed by pancreas., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |