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ITN2358

ITN2358
  • Catalog: ITN2358
  • Gene/Protein: TREML1 TLT1 UNQ1825/PRO3438
  • Product Description: Immunotag™ TRML1 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ TRML1 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein TRML1
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein . at AA range: 30-110
Specificity TRML1 Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name TREML1 TLT1 UNQ1825/PRO3438
Accession No. Q86YW5 Q8K558
Description triggering receptor expressed on myeloid cells like 1(TREML1) Homo sapiens This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012],
Subcellular Localization cytoplasm,plasma membrane,cell surface,integral component of membrane,platelet alpha granule,
Protein Function function:Cell surface receptor that may play a role in the innate and adaptive immune response.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subcellular location:Sequestered in cytoplasmic vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be released into the serum by proteolysis.,subunit:When phosphorylated, interacts with PTPN6 (By similarity). When phosphorylated, interacts with PTPN11.,tissue specificity:Detected in platelets, monocytic leukemia and in T-cell leukemia.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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