ITN2453
ITN2453
- Catalog: ITN2453
- Gene/Protein: PF4V1 CXCL4V1 SCYB4V1
- Product Description: Immunotag™ PF4V Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | PF4V |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein . at AA range: 54-103 |
Specificity | PF4V Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | PF4V1 CXCL4V1 SCYB4V1 |
Accession No. | P10720 |
Description | platelet factor 4 variant 1(PF4V1) Homo sapiens The protein encoded by this gene is a chemokine that is highly similar to platelet factor 4. The encoded protein displays a strong antiangiogenic function and is regulated by chemokine (C-X-C motif) receptor 3. This protein also impairs tumor growth and can protect against blood-retinal barrier breakdown in diabetes patients. [provided by RefSeq, Nov 2015], |
Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Chemokine, |
Subcellular Localization | extracellular space, |
Protein Function | function:Inhibitor of angiogenesis. Inhibitor of endothelial cell chemotaxis (in vitro).,mass spectrometry:Platelet factor 4 variant PubMed:15459074,mass spectrometry:Platelet factor 4 variant(4-74) PubMed:15459074,mass spectrometry:Platelet factor 4 variant(5-74) PubMed:15459074,mass spectrometry:Platelet factor 4 variant(6-74) PubMed:15459074,PTM:The N-terminal processed forms of platelet factor 4 variant seems to be produced by proteolytic cleavage. The most abundant form is Platelet factor 4 variant(5-74).,similarity:Belongs to the intercrine alpha (chemokine CxC) family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |