ITN2536
ITN2536
- Catalog: ITN2536
- Gene/Protein: OXGR1 GPR80 GPR99 P2RY15 P2Y15
- Product Description: Immunotag™ OXGR1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | OXGR1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from human protein, at AA range: 130-210 |
| Specificity | OXGR1 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | OXGR1 GPR80 GPR99 P2RY15 P2Y15 |
| Accession No. | Q96P68 Q6IYF8 Q6Y1R5 |
| Description | oxoglutarate receptor 1(OXGR1) Homo sapiens This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016], |
| Protein Expression | Placenta,Thyroid,Tongue,Trachea, |
| Subcellular Localization | plasma membrane,integral component of membrane, |
| Protein Function | caution:Was originally (Ref.5) thought to be a P2Y receptor.,function:Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Detected in kidney and, to a lower extend, in placenta. Not detected in brain tissues including the frontal cortex, caudate putamen, thalamus, hypothalamus, hippocampus or pons., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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