ITN2673
ITN2673
- Catalog: ITN2673
- Gene/Protein: P2RY1
- Product Description: Immunotag™ P2RY1 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | P2RY1 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 130-210 |
Specificity | P2RY1 Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | P2RY1 |
Accession No. | P47900 P49650 P49651 |
Description | purinergic receptor P2Y1(P2RY1) Homo sapiens The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
Protein Expression | Blood,Brain,Lung,Placenta,Platelet, |
Subcellular Localization | mitochondrion,plasma membrane,integral component of plasma membrane,cell surface,postsynaptic density,basolateral plasma membrane,apical plasma membrane,dendrite,cell body,postsynaptic membrane, |
Protein Function | function:Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.,induction:Repressed by the P2Y1 receptor-specific antagonists A3P5PS, A3P5P and A2P5P. These inhibit calcium ion mobilization and shape change in platelets.,similarity:Belongs to the G-protein coupled receptor 1 family., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |