ITN2680
ITN2680
- Catalog: ITN2680
- Gene/Protein: ADCYAP1R1
- Product Description: Immunotag™ PACR Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | PACR |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,ELISA |
Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
Concentration | 1 mg/ml |
Reactive Species | Human,Rat,Mouse |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from human protein, at AA range: 80-160 |
Specificity | PACR Polyclonal Antibody detects endogenous levels of protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
Gene Name | ADCYAP1R1 |
Accession No. | P41586 P70205 P32215 |
Description | ADCYAP receptor type I(ADCYAP1R1) Homo sapiens This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction, |
Protein Expression | Brain,Osteoblast,Pituitary,Placenta,Testicle, |
Subcellular Localization | endosome,rough endoplasmic reticulum,plasma membrane,integral component of plasma membrane,caveola,bicellular tight junction,cell surface,membrane,integral component of membrane,neuron projection,receptor complex, |
Protein Function | function:This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.,similarity:Belongs to the G-protein coupled receptor 2 family.,tissue specificity:Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |