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ITN2680

ITN2680
  • Catalog: ITN2680
  • Gene/Protein: ADCYAP1R1
  • Product Description: Immunotag™ PACR Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ PACR Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PACR
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 80-160
Specificity PACR Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name ADCYAP1R1
Accession No. P41586 P70205 P32215
Description ADCYAP receptor type I(ADCYAP1R1) Homo sapiens This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010],
Cell Pathway/ Category Neuroactive ligand-receptor interaction,
Protein Expression Brain,Osteoblast,Pituitary,Placenta,Testicle,
Subcellular Localization endosome,rough endoplasmic reticulum,plasma membrane,integral component of plasma membrane,caveola,bicellular tight junction,cell surface,membrane,integral component of membrane,neuron projection,receptor complex,
Protein Function function:This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.,similarity:Belongs to the G-protein coupled receptor 2 family.,tissue specificity:Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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