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ITN2685

ITN2685
  • Gene/Protein: PTH2R PTHR2
  • Product Description: Immunotag™ PTH2R Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ PTH2R Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein PTH2R
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Rat,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from human protein, at AA range: 160-240
Specificity PTH2R Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name PTH2R PTHR2
Accession No. P49190 Q91V95 P70555
Description parathyroid hormone 2 receptor(PTH2R) Homo sapiens The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
Cell Pathway/ Category Neuroactive ligand-receptor interaction,
Protein Expression Brain,Retina,
Subcellular Localization plasma membrane,integral component of plasma membrane,membrane,integral component of membrane,
Protein Function function:This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Binds to TIPF39/TIP39.,tissue specificity:Expressed abundantly in brain and pancreas. Also expressed in the testis.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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