ITN2987
ITN2987
- Catalog: ITN2987
- Gene/Protein: RAMP2
- Product Description: Immunotag™ RAMP2 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | RAMP2 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,ELISA |
| Recommended Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | RAMP2 Polyclonal Antibody detects endogenous levels of protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Gene Name | RAMP2 |
| Accession No. | O60895 Q9WUP0 Q9JHJ1 |
| Description | receptor activity modifying protein 2(RAMP2) Homo sapiens The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq, Jul 2008], |
| Cell Pathway/ Category | Vascular smooth muscle contraction, |
| Protein Expression | Heart,Neuroblastoma,Pancreas, |
| Subcellular Localization | intracellular,cytoplasm,lysosome,plasma membrane,integral component of plasma membrane,clathrin-coated pit,cell surface,integral component of membrane,receptor complex, |
| Protein Function | function:Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.,similarity:Belongs to the RAMP family.,subunit:Heterodimer of CALCRL and RAMP2.,tissue specificity:Strongly expressed in lung, breast, immune system and fetal tissues., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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