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ITN3019

ITN3019
  • Gene/Protein: C8G
  • Product Description: Immunotag™ CO8G Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ CO8G Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CO8G
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution WB 1:500-2000 ELISA 1:5000-20000
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen Synthesized peptide derived from part region of human protein
Specificity CO8G Polyclonal Antibody detects endogenous levels of protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Gene Name C8G
Accession No. P07360 Q8VCG4
Description complement C8 gamma chain(C8G) Homo sapiens The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity. [provided by RefSeq, Jul 2011],
Cell Pathway/ Category Complement and coagulation cascades,Prion diseases,Systemic lupus erythematosus,
Protein Expression Blood,Colon,Liver,
Subcellular Localization extracellular region,membrane attack complex,extracellular exosome,blood microparticle,
Protein Function function:C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol.,similarity:Belongs to the calycin superfamily. Lipocalin family.,subunit:C8 is composed of three chains: alpha, beta and gamma. The alpha and gamma chains are disulfide bonded.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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