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ITP0530

ITP0530
  • Catalog: ITP0530
  • Gene/Protein: PECAM1
  • Product Description: Immunotag™ CD31 (phospho Tyr713) Polyclonal Antibody
490.0000
Price in reward points: 490

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Immunotag™ CD31 (phospho Tyr713) Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CD31 (Tyr713)
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,IF,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human PECAM-1 around the phosphorylation site of Tyr713. AA range:686-735
Specificity Phospho-CD31 (Y713) Polyclonal Antibody detects endogenous levels of CD31 protein only when phosphorylated at Y713.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name PECAM1
Accession No. P16284 Q08481
Alternate Names PECAM1; Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD antigen CD31
Description platelet and endothelial cell adhesion molecule 1(PECAM1) Homo sapiens The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010],
Cell Pathway/ Category Cell adhesion molecules (CAMs),Leukocyte transendothelial migration,
Protein Expression Brain,Liver,Platelet,
Subcellular Localization extracellular space,plasma membrane,external side of plasma membrane,integral component of membrane,cell junction,smooth muscle contractile fiber,platelet alpha granule membrane,membrane raft,extracellular exosome,
Protein Function function:This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions.,online information:CD31 entry,online information:PECAM-1,online information:The Singapore human mutation and polymorphism database,PTM:Phosphorylated on Ser and Tyr residues after cellular activation.,similarity:Contains 6 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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