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ITP0675

ITP0675
ITP0675
ITP0675
  • Gene/Protein: Tnni3
  • Product Description: Immunotag™ Troponin I-C (phospho Ser22/S23) Polyclonal Antibody
357.0000
Price in reward points: 357

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Immunotag™ Troponin I-C (phospho Ser22/S23) Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein Troponin I-C (Ser22/S23)
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Mouse,Rat
Host Species Rabbit
Immunogen Synthesized phospho-peptide around the phosphorylation site of human Troponin I-C (phospho Ser22/S23)
Specificity Phospho-Troponin I-C (S22/S23) Polyclonal Antibody detects endogenous levels of Troponin I-C protein only when phosphorylated at S22/S23.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name Tnni3
Accession No. P23693
Alternate Names TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I
Description Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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