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ITP0982

ITP0982
  • Catalog: ITP0982
  • Gene/Protein: C5AR1
  • Product Description: Immunotag™ CD88 (phospho Ser338) Polyclonal Antibody
490.0000
Price in reward points: 490

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Immunotag™ CD88 (phospho Ser338) Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CD88 (Ser338)
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human CD88/C5aR around the phosphorylation site of Ser338. AA range:301-350
Specificity Phospho-CD88 (S338) Polyclonal Antibody detects endogenous levels of CD88 protein only when phosphorylated at S338.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name C5AR1
Accession No. P21730 P30993
Alternate Names C5AR1; C5AR; C5R1; C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD antigen CD88
Description function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Cell Pathway/ Category Neuroactive ligand-receptor interaction,Complement and coagulation cascades,
Protein Expression Brain,
Subcellular Localization plasma membrane,integral component of plasma membrane,cell surface,cytoplasmic, membrane-bounded vesicle,basolateral plasma membrane,cytoplasmic vesicle,apical part of cell,
Protein Function function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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