ITP1040
ITP1040
- Catalog: ITP1040
- Gene/Protein: CSNK1G1/CSNK1G2/CSNK1G3
- Product Description: Immunotag™ Casein Kinase Iγ1/2/3 (phospho Tyr263) Polyclonal Antibody
490.0000
Price in reward points: 490
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CK Iγ1/2/3 (Tyr263) |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized phospho-peptide around the phosphorylation site of human Casein Kinase Iγ1/2/3 (phospho Tyr263) |
| Specificity | Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody detects endogenous levels of Casein Kinase Iγ1/2/3 protein only when phosphorylated at Y263. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CSNK1G1/CSNK1G2/CSNK1G3 |
| Accession No. | Q9HCP0/P78368/Q9Y6M4 Q62761/Q62762/Q62763 |
| Alternate Names | CSNK1G1; Casein kinase I isoform gamma-1; CKI-gamma 1; CSNK1G2; CK1G2; Casein kinase I isoform gamma-2; CKI-gamma 2; CSNK1G3; Casein kinase I isoform gamma-3; CKI-gamma 3 |
| Description | casein kinase 1 gamma 1(CSNK1G1) Homo sapiens This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016], |
| Cell Pathway/ Category | Hedgehog, |
| Protein Expression | Brain,Muscle,Pooled, |
| Subcellular Localization | nucleus,cytoplasm,integral component of membrane, |
| Protein Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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