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ITT0040

ITT0040
ITT0040
ITT0040
  • Catalog: ITT0040
  • Gene/Protein: AASDHPPT
  • Product Description: Immunotag™ AASD-PPT Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ AASD-PPT Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein AASD-PPT
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from AASD-PPT, at AA range: 30-110
Specificity AASD-PPT Polyclonal Antibody detects endogenous levels of AASD-PPT protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name AASDHPPT
Accession No. Q9NRN7 Q9CQF6 B2RYJ4
Alternate Names AASDHPPT; CGI-80; HAH-P; HSPC223; x0005; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; 4'-phosphopantetheinyl transferase; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD-PPT;
Description aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase(AASDHPPT) Homo sapiens The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Lysine biosynthesis,Lysine degradation,
Protein Expression Adrenal gland,Brain,Cajal-R
Subcellular Localization cytosol,extracellular exosome,
Protein Function catalytic activity:CoA-[4'-phosphopantetheine] + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein].,cofactor:Binds 1 magnesium ion.,function:Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the P-Pant transferase superfamily. AcpS family.,subunit:Monomer. Interacts with FASN.,tissue specificity:Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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