ITT0040
ITT0040
- Catalog: ITT0040
- Gene/Protein: AASDHPPT
- Product Description: Immunotag™ AASD-PPT Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | AASD-PPT |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from AASD-PPT, at AA range: 30-110 |
Specificity | AASD-PPT Polyclonal Antibody detects endogenous levels of AASD-PPT protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | AASDHPPT |
Accession No. | Q9NRN7 Q9CQF6 B2RYJ4 |
Alternate Names | AASDHPPT; CGI-80; HAH-P; HSPC223; x0005; L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; 4'-phosphopantetheinyl transferase; Alpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferase; AASD-PPT; |
Description | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase(AASDHPPT) Homo sapiens The protein encoded by this gene is similar to Saccharomyces cerevisiae LYS5, which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine. Yeast alpha-aminoadipate dehydrogenase converts alpha-biosynthetic-aminoadipate semialdehyde to alpha-aminoadipate. It has been suggested that defects in the human gene result in pipecolic acidemia. [provided by RefSeq, Jul 2008], |
Cell Pathway/ Category | Lysine biosynthesis,Lysine degradation, |
Protein Expression | Adrenal gland,Brain,Cajal-R |
Subcellular Localization | cytosol,extracellular exosome, |
Protein Function | catalytic activity:CoA-[4'-phosphopantetheine] + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein].,cofactor:Binds 1 magnesium ion.,function:Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the P-Pant transferase superfamily. AcpS family.,subunit:Monomer. Interacts with FASN.,tissue specificity:Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |