ITT0060
ITT0060
- Catalog: ITT0060
- Gene/Protein: ABHD4
- Product Description: Immunotag™ ABHD4 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | ABHD4 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human ABHD4. AA range:251-300 |
Specificity | ABHD4 Polyclonal Antibody detects endogenous levels of ABHD4 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | ABHD4 |
Accession No. | Q8TB40 Q8VD66 |
Alternate Names | ABHD4; Abhydrolase domain-containing protein 4; Alpha/beta-hydrolase 4; Lyso-N-acylphosphatidylethanolamine lipase |
Description | caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue.,function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.,similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily., |
Protein Expression | Cervix, |
Subcellular Localization | endoplasmic reticulum membrane,lipid particle, |
Protein Function | caution:Thr-291 is present instead of the conserved His which is expected to be an active site residue.,function:Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.,similarity:Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |