menu
Your Cart

ITT0069

ITT0069
  • Catalog: ITT0069
  • Gene/Protein: ACAD11
  • Product Description: Immunotag™ ACAD-11 Polyclonal Antibody
385.0000
Price in reward points: 385

Available Options

Immunotag™ ACAD-11 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein ACAD-11
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,IHC-p,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human ACAD11. AA range:381-430
Specificity ACAD-11 Polyclonal Antibody detects endogenous levels of ACAD-11 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name ACAD11
Accession No. Q709F0 Q80XL6
Alternate Names ACAD11; Acyl-CoA dehydrogenase family member 11; ACAD-11
Description acyl-CoA dehydrogenase family member 11(ACAD11) Homo sapiens This gene encodes an acyl-CoA dehydrogenase enzyme with a preference for carbon chain lengths between 20 and 26. Naturally occurring read-through transcription occurs between the upstream gene NPHP3 (nephronophthisis 3 (adolescent)) and this gene. [provided by RefSeq, Aug 2015],
Protein Expression Brain,Cervix,Fetal kidney,Lymph node,Mammary gland,PCR rescued clon
Subcellular Localization nucleus,mitochondrial inner membrane,peroxisome,mitochondrial membrane,
Protein Function Additional isoforms seem to exist,disease:Defects in NPHP3 are a cause of renal-hepatic-pancreatic dysplasia (RHPD) [MIM:208540]. RHPD is an autosomal recessive disorder with variable expression, and patients surviving the neonatal period progress to renal and hepatic failure which can be treated successfully with combined liver-kidney transplantation.,disease:Defects in NPHP3 are the cause of nephronophthisis type 3 (NPHP3) [MIM:604387]; also known as adolescent nephronophthisis. NPHP3 is a autosomal recessive disorder resulting in end-stage renal disease. It is characterized by polyuria, polydipsia, anemia. Onset of terminal renal failure occurr significantly later (median age, 19 years) than in juvenile nephronophthisis. Renal pathology is characterized by alterations of tubular basement membranes, tubular atrophy and dilatation, sclerosing tubulointerstitial nephropathy, and renal cyst development predominantly at the corticomedullary junction.,function:May participate in mechanosensation in the primary cilium of kidney cells.,similarity:Belongs to the acyl-CoA dehydrogenase family.,similarity:Contains 11 TPR repeats.,subunit:Interacts with NPHP1.,tissue specificity:Widely expressed at low level. Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at very low level in brain and lung.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
English_US
Danish
Dutch
English_UK
French
German
Spanish
Norwegian
Portuguese
Finnish
Swedish
Polish

Write a review

Note: HTML is not translated!
Bad Good
Captcha

CONNECT WITH US