ITT0337
ITT0337
- Catalog: ITT0337
- Gene/Protein: ARPP21
- Product Description: Immunotag™ ARPP-21 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | ARPP-21 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARPP21. AA range:211-260 |
| Specificity | ARPP-21 Polyclonal Antibody detects endogenous levels of ARPP-21 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ARPP21 |
| Accession No. | Q9UBL0 Q9DCB4 |
| Alternate Names | ARPP21; TARPP; cAMP-regulated phosphoprotein 21; ARPP-21; Thymocyte cAMP-regulated phosphoprotein |
| Description | cAMP regulated phosphoprotein 21(ARPP21) Homo sapiens This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012], |
| Protein Expression | Brain,Caudate nucleus,Hypothalamus,Kidney,Lung,T-cell,Testis, |
| Subcellular Localization | cytoplasm, |
| Protein Function | function:Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.,PTM:Isoform 1 is methylated by CARM1 in immature thymocytes.,PTM:Phosphorylation at Ser-56 favors interaction with CALM1.,similarity:Contains 1 R3H domain.,subunit:Interacts with CALM1.,tissue specificity:Isoform 2 is expressed in brain. Isoform 1 is present in immature thymocytes (at protein level)., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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