ITT0342
ITT0342
- Catalog: ITT0342
- Gene/Protein: ARR3
- Product Description: Immunotag™ Arrestin-C Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Arrestin-C |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,IF,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARRC. AA range:339-388 |
| Specificity | Arrestin-C Polyclonal Antibody detects endogenous levels of Arrestin-C protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | ARR3 |
| Accession No. | P36575 Q9EQP6 |
| Alternate Names | ARR3; ARRX; CAR; Arrestin-C; Cone arrestin; C-arrestin; cArr; Retinal cone arrestin-3; X-arrestin |
| Description | arrestin 3(ARR3) Homo sapiens The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016], |
| Protein Expression | Eye,Retina, |
| Subcellular Localization | photoreceptor outer segment,photoreceptor inner segment,cytoplasm,synapse, |
| Protein Function | function:May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins.,similarity:Belongs to the arrestin family.,tissue specificity:Inner and outer segments, and the inner plexiform regions of the retina., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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