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ITT0553

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ITT0553
ITT0553
  • Gene/Protein: CEBPB
  • Product Description: Immunotag™ C/EBP β Polyclonal Antibody
280.0000
Price in reward points: 294

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Immunotag™ C/EBP β Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein C/EBP β
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IF,WB,IHC-p,ELISA
Recommended Dilution IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human,Mouse,Rat
Host Species Rabbit
Immunogen Synthesized peptide derived from C/EBP β, at AA range: 180-260
Specificity C/EBP β Polyclonal Antibody detects endogenous levels of C/EBP β protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name CEBPB
Accession No. P17676 P28033 P21272
Alternate Names CEBPB; LAP; TCF5; PP9092; CCAAT/enhancer-binding protein beta; C/EBP beta; Liver activator protein; Nuclear factor NF-IL6; Transcription factor 5; TCF-5
Description CCAAT/enhancer binding protein beta(CEBPB) Homo sapiens This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013],
Cell Pathway/ Category Stem cell pathway, Protein_Acetylation
Protein Expression Muscle,Ovary,Placenta,Skin,
Subcellular Localization condensed chromosome, centromeric region,nuclear chromatin,nucleus,nucleoplasm,cytoplasm,nuclear matrix,CHOP-C/EBP complex,
Protein Function function:Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses. Specifically binds to an IL-1 response element in the IL-6 gene. NF-IL6 also binds to regulatory regions of several acute-phase and cytokines genes. It probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'.,PTM:Sumoylated by polymeric chains of SUMO2 or SUMO3.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha, delta and gamma. Interacts with TRIM28 and PTGES2.,tissue specificity:Expressed at low levels in the lung, kidney and spleen.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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