ITT0556
ITT0556
- Catalog: ITT0556
- Gene/Protein: CEBPD/CEBPE
- Product Description: Immunotag™ C/EBP δ/ε Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | C/EBP δ/ε |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,IF,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human,Mouse,Rat |
Host Species | Rabbit |
Immunogen | Synthesized peptide derived from C/EBP δ/ε, at AA range: 140-220 |
Specificity | C/EBP δ/ε Polyclonal Antibody detects endogenous levels of C/EBP δ/ε protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CEBPD/CEBPE |
Accession No. | P49716/Q15744 Q03484/P56261 |
Alternate Names | CEBPD; CCAAT/enhancer-binding protein delta; C/EBP delta; Nuclear factor NF-IL6-beta; NF-IL6-beta; CEBPE; CCAAT/enhancer-binding protein epsilon; C/EBP epsilon |
Description | CCAAT/enhancer binding protein delta(CEBPD) Homo sapiens The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010], |
Protein Expression | Cerebellum,Placenta, |
Subcellular Localization | nucleus, |
Protein Function | function:C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages.,similarity:Belongs to the bZIP family. C/EBP subfamily.,similarity:Contains 1 bZIP domain.,subunit:Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha. Interacts with SPI1/PU.1., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |