ITT0568
ITT0568
- Catalog: ITT0568
- Gene/Protein: C3AR1
- Product Description: Immunotag™ C3aR Polyclonal Antibody
385.0000
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Antibody Specification | |
Datasheet | |
Target Protein | C3aR |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | IHC-p,IF,ELISA |
Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human C3AR1. AA range:175-224 |
Specificity | C3aR Polyclonal Antibody detects endogenous levels of C3aR protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | C3AR1 |
Accession No. | Q16581 O09047 |
Alternate Names | C3AR1; AZ3B; C3R1; HNFAG09; C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R |
Description | complement C3a receptor 1(C3AR1) Homo sapiens C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016], |
Cell Pathway/ Category | Neuroactive ligand-receptor interaction,Complement and coagulation cascades, |
Protein Expression | Caudate nucleus,Cord blood,Lung,Synovial membrane, |
Subcellular Localization | plasma membrane,integral component of plasma membrane,integral component of membrane, |
Protein Function | function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues., |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |