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ITT0568

ITT0568
  • Catalog: ITT0568
  • Gene/Protein: C3AR1
  • Product Description: Immunotag™ C3aR Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ C3aR Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein C3aR
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application IHC-p,IF,ELISA
Recommended Dilution Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen The antiserum was produced against synthesized peptide derived from human C3AR1. AA range:175-224
Specificity C3aR Polyclonal Antibody detects endogenous levels of C3aR protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name C3AR1
Accession No. Q16581 O09047
Alternate Names C3AR1; AZ3B; C3R1; HNFAG09; C3a anaphylatoxin chemotactic receptor; C3AR; C3a-R
Description complement C3a receptor 1(C3AR1) Homo sapiens C3a is an anaphylatoxin released during activation of the complement system. The protein encoded by this gene is an orphan G protein-coupled receptor for C3a. Binding of C3a by the encoded receptor activates chemotaxis, granule enzyme release, superoxide anion production, and bacterial opsonization. [provided by RefSeq, May 2016],
Cell Pathway/ Category Neuroactive ligand-receptor interaction,Complement and coagulation cascades,
Protein Expression Caudate nucleus,Cord blood,Lung,Synovial membrane,
Subcellular Localization plasma membrane,integral component of plasma membrane,integral component of membrane,
Protein Function function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Among the sulfation sites Tyr-174 is essential for binding of C3a anaphylatoxin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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