ITT0610
ITT0610
- Catalog: ITT0610
- Gene/Protein: S100A11
- Product Description: Immunotag™ Calgizzarin Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Calgizzarin |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | IHC-p,ELISA |
| Recommended Dilution | Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from Calgizzarin, at AA range: 30-110 |
| Specificity | Calgizzarin Polyclonal Antibody detects endogenous levels of Calgizzarin protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | S100A11 |
| Accession No. | P31949 P50543 Q6B345 |
| Alternate Names | S100A11; MLN70; S100C; Protein S100-A11; Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70; Protein S100-C; S100 calcium-binding protein A11 |
| Description | S100 calcium binding protein A11(S100A11) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008], |
| Protein Expression | Brain,Epithelium,Keratinocyte,Lung,Mammary carcinoma,Placenta,Urina |
| Subcellular Localization | ruffle,extracellular space,nucleus,cytoplasm,cell-cell adherens junction,extracellular exosome, |
| Protein Function | function:Facilitates the differentiation and the cornification of keratinocytes.,miscellaneous:Binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins.,PTM:Phosphorylation at Thr-10 by PRKCA significantly suppresses homodimerization and promotes association with NCL/nucleolin which induces nuclear translocation.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer; disulfide-linked., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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