ITT0638
ITT0638
- Catalog: ITT0638
- Gene/Protein: CTF1
- Product Description: Immunotag™ Cardiotrophin-1 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | Cardiotrophin-1 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse,Rat |
| Host Species | Rabbit |
| Immunogen | Synthesized peptide derived from the N-terminal region of human Cardiotrophin-1 |
| Specificity | Cardiotrophin-1 Polyclonal Antibody detects endogenous levels of Cardiotrophin-1 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CTF1 |
| Accession No. | Q16619 Q60753 Q63086 |
| Alternate Names | CTF1; Cardiotrophin-1; CT-1 |
| Description | cardiotrophin 1(CTF1) Homo sapiens The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008], |
| Cell Pathway/ Category | Cytokine-cytokine receptor interaction,Jak_STAT, |
| Protein Expression | Brain,Heart,Lung, |
| Subcellular Localization | extracellular region,extracellular space, |
| Protein Function | function:Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.,similarity:Belongs to the IL-6 superfamily.,tissue specificity:Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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