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ITT0719

ITT0719
ITT0719
ITT0719
  • Catalog: ITT0719
  • Gene/Protein: CSF2RA
  • Product Description: Immunotag™ CD116 Polyclonal Antibody
385.0000
Price in reward points: 385

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Immunotag™ CD116 Polyclonal Antibody
Antibody Specification
Datasheet
Target Protein CD116
Clonality Polyclonal
Storage/Stability -20°C/1 year
Application WB,ELISA
Recommended Dilution Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Concentration 1 mg/ml
Reactive Species Human
Host Species Rabbit
Immunogen Synthesized peptide derived from the Internal region of human CD116.
Specificity CD116 Polyclonal Antibody detects endogenous levels of CD116 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Gene Name CSF2RA
Accession No. P15509 Q00941
Alternate Names CSF2RA; CSF2R; CSF2RY; Granulocyte-macrophage colony-stimulating factor receptor subunit alpha; GM-CSF-R-alpha; GMCSFR-alpha; GMR-alpha; CDw116; CD antigen CD116
Description colony stimulating factor 2 receptor alpha subunit(CSF2RA) Homo sapiens The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq, Jul 2008],
Cell Pathway/ Category Cytokine-cytokine receptor interaction,Jak_STAT,Hematopoietic cell lineage,Pathways in cancer,
Protein Expression Blood,Placenta,Synovial membrane tissue,Uterus,
Subcellular Localization extracellular region,intracellular,plasma membrane,integral component of plasma membrane,membrane,
Protein Function domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Belongs to the type I cytokine receptor family. Type 5 subfamily.,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.,
Usage For Research Use Only! Not for diagnostic or therapeutic procedures.
Material Safety Data Sheet
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