ITT0977
ITT0977
- Catalog: ITT0977
- Gene/Protein: CLN6
- Product Description: Immunotag™ CLN6 Polyclonal Antibody
385.0000
Price in reward points: 385
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Antibody Specification | |
Datasheet | |
Target Protein | CLN6 |
Clonality | Polyclonal |
Storage/Stability | -20°C/1 year |
Application | WB,IHC-p,ELISA |
Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications. |
Concentration | 1 mg/ml |
Reactive Species | Human |
Host Species | Rabbit |
Immunogen | The antiserum was produced against synthesized peptide derived from human CLN6. AA range:221-270 |
Specificity | CLN6 Polyclonal Antibody detects endogenous levels of CLN6 protein. |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Gene Name | CLN6 |
Accession No. | Q9NWW5 |
Alternate Names | CLN6; Ceroid-lipofuscinosis neuronal protein 6; Protein CLN6 |
Description | ceroid-lipofuscinosis, neuronal 6, late infantile, variant(CLN6) Homo sapiens This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function. [provided by RefSeq, Oct 2008], |
Protein Expression | Epithelium,Lung,Urinary bladder, |
Subcellular Localization | endoplasmic reticulum,endoplasmic reticulum lumen,endoplasmic reticulum membrane,membrane,integral component of membrane, |
Protein Function | disease:Defects in CLN6 are the cause of variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL) [MIM:601780].,online information:Neural Ceroid Lipofuscinoses mutation db, |
Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |