ITT1002
ITT1002
- Catalog: ITT1002
- Gene/Protein: CNOT7
- Product Description: Immunotag™ CNOT7 Polyclonal Antibody
385.0000
Price in reward points: 385
| Antibody Specification | |
| Datasheet | 
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| Target Protein | CNOT7 |
| Clonality | Polyclonal |
| Storage/Stability | -20°C/1 year |
| Application | WB,IHC-p,ELISA |
| Recommended Dilution | Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications. |
| Concentration | 1 mg/ml |
| Reactive Species | Human,Mouse |
| Host Species | Rabbit |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CNOT7. AA range:10-59 |
| Specificity | CNOT7 Polyclonal Antibody detects endogenous levels of CNOT7 protein. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Gene Name | CNOT7 |
| Accession No. | Q9UIV1 Q60809 |
| Alternate Names | CNOT7; CAF1; CCR4-NOT transcription complex subunit 7; BTG1-binding factor 1; CCR4-associated factor 1; CAF-1 |
| Description | CCR4-NOT transcription complex subunit 7(CNOT7) Homo sapiens The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016], |
| Cell Pathway/ Category | RNA degradation, |
| Protein Expression | Embryo,Lymph,Placenta,Prostate,Testis, |
| Subcellular Localization | cytoplasmic mRNA processing body,nucleus,nucleoplasm,cytosol,membrane,CCR4-NOT complex, |
| Protein Function | function:Ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.,similarity:Belongs to the CAF1 family.,subunit:Interacts with TOB1., |
| Usage | For Research Use Only! Not for diagnostic or therapeutic procedures. |
| Material Safety Data Sheet | |
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